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Stelara (Ustekinumab)

  Stelara (Ustekinumab)

Stelara (Ustekinumab)

Stelara (Ustekinumab) is a prescription medication used for the treatment of several chronic inflammatory conditions, including moderate to severe plaque psoriasis, active psoriatic arthritis, and moderate to severe Crohn's disease in adults. It is designed to modulate the immune system by targeting specific proteins involved in the inflammatory process.

Why Choose Stelara (Ustekinumab)?

  • Targeted Treatment: Specifically targets the proteins interleukin-12 (IL-12) and interleukin-23 (IL-23) which are key drivers of immune-mediated inflammatory diseases.
  • Improves Skin Clarity: Significantly reduces the appearance of psoriatic plaques.
  • Joint Symptom Relief: Helps relieve joint pain and stiffness for those with psoriatic arthritis.
  • Long-term Control: Provides sustained symptom control with periodic dosing.
  • Gastrointestinal Relief: Helps reduce symptoms of Crohn's disease such as diarrhea, stomach pain, and weight loss.

How to Use Stelara (Ustekinumab)?

  • Administration: Stelara is first given as an intravenous (IV) infusion by a healthcare professional. This allows for the full dose to be delivered directly into the bloodstream.
  • Duration: The initial IV infusion is typically completed in approximately one hour.
  • Method: After the initial IV infusion, Stelara is usually administered as a subcutaneous injection.
  • Frequency: The injections are generally scheduled every 8 weeks, depending on the specific condition being treated and the patient's response to the medication.
  • Preparation: Ensure the medication is at room temperature and check the liquid in the pre-filled syringe or pen for any particles or discoloration before administration.
  • Injection Sites: Suitable sites for injection include the thighs, lower abdomen (excluding the area 2 inches around the navel), or the upper arms if not self-injecting.

Important Safety Information about Stelara

  • Infection Risk: Increases the risk of infections; patients should be tested for tuberculosis before starting treatment.
  • Allergic Reactions: Can cause serious allergic reactions. Symptoms such as swelling, difficulty breathing, and severe rash require immediate medical attention.
  • Vaccinations: Live vaccines should be avoided during treatment; consult with a healthcare provider before receiving any vaccine.
  • Pregnancy and Nursing: Discuss with a healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
  • Storage: Store Stelara in a refrigerator, protected from light. Do not freeze.

Fact Table

 
Facts Details
Generic Name Ustekinumab
Brand Name Stelara
Drug Class Monoclonal antibody
FDA Approval Year 2009
Indications - Moderate to severe plaque psoriasis - Active psoriatic arthritis - Moderate to severe Crohn's disease in adults
Administration Route - Initial dose: Intravenous (IV) infusion - Follow-up doses: Subcutaneous injection
Dosage Form - IV infusion- Pre-filled syringe or autoinjector for subcutaneous injection
Recommended Dosage - Varies based on condition and patient response; typically every 8 weeks after initial doses
Common Side Effects - Respiratory infections - Headaches - Fatigue - Injection site reactions - Nausea
Major Safety Warnings - Increased risk of infections - Potential for serious allergic reactions - Avoidance of live vaccines during treatment
Pregnancy Category Category B (No evidence of risk in humans)
Storage Instructions Store in a refrigerator, protect from light, do not freeze

Common Side Effects

Like all medications, Stelara (Ustekinumab) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
  • Respiratory Infections
  • Headaches
  • Fatigue
  • Injection Site Reactions
  • Nausea
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Stelara (Ustekinumab)?

You can order Stelara (Ustekinumab) using these methods on our website:
  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills
Visit our How to order page.
Dr. Conor Sheehy, PharmD, BCPS

Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.

Please note that due to government rules and regulations, orders may not exceed 3 months in supply.
Please call 1-800-258-0477 or email us if you have any questions or concerns.