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Benlysta (Belimumab)

Benlysta (Belimumab)

Benlysta (Belimumab) is a prescription medication used to treat certain forms of lupus, including systemic lupus erythematosus (SLE) and lupus nephritis. It works by targeting a protein in the immune system that is believed to play a role in the abnormal immune response seen in lupus. Benlysta helps reduce disease activity, flare-ups, and the need for steroids, offering long-term relief and better disease control when used alongside standard therapy.

Why Choose Benlysta (Belimumab)?

  • Specifically designed for treating systemic lupus erythematosus (SLE) and lupus nephritis
  • Helps reduce lupus flares and disease activity
  • Can minimize reliance on corticosteroids
  • Available in both intravenous (IV) and subcutaneous (SC) formulations for flexible treatment
  • Clinically proven to improve patient-reported quality of life over time

How to Use Benlysta (Belimumab)?

  • Always use Benlysta exactly as prescribed by your healthcare provider
  • For IV use, treatment is administered by a healthcare professional at a medical facility
  • For SC use, it is typically injected once a week at home – ensure you're trained properly before self-injecting
  • Store the medication in the refrigerator and protect it from light; do not freeze
  • Allow the medication to reach room temperature before injecting
  • Rotate injection sites to avoid skin irritation
  • Do not miss doses; if you do, contact your doctor for instructions

Important Safety Information about Benlysta

  • Benlysta is not recommended for people with severe active central nervous system lupus
  • Inform your doctor if you have an active infection or a history of chronic infections before starting
  • May increase your risk of serious infections and allergic reactions
  • Tell your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding
  • Live vaccines should be avoided during treatment with Benlysta
  • Regular monitoring and follow-up appointments are important to ensure safe and effective use

Fact Table

 
Facts Details
Brand Name Benlysta
Generic Name Belimumab
Drug Class Monoclonal antibody (BLyS-specific inhibitor)
Used For Systemic Lupus Erythematosus (SLE), Lupus Nephritis
Route of Administration Intravenous (IV) infusion or Subcutaneous (SC) injection
Dosage Form Solution for injection
Typical Dosage IV: 10 mg/kg every 2 weeks for 3 doses, then every 4 weeks SC: 200 mg once weekly
How it Works Inhibits B-lymphocyte stimulator (BLyS), reducing abnormal B-cell activity
Onset of Action May take several weeks to notice improvement
Storage Requirements Refrigerate at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light
Prescription Required Yes
Availability at PharmaServe Yes, Available via prescription with fast delivery and secure checkout

Common Side Effects

Like all medications, Benlysta (Belimumab) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
  • Nausea
  • Diarrhea
  • Fever
  • Insomnia (trouble sleeping)
  • Nasal congestion or sore throat
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Benlysta (Belimumab)?

You can order Benlysta (Belimumab) using these methods on our website:
  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills
Visit our How to order page.
Dr. Conor Sheehy, PharmD, BCPS

Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.

Please note that due to government rules and regulations, orders may not exceed 3 months in supply.
Please call 1-800-258-0477 or email us if you have any questions or concerns.